Functional enrichment analysis for a set of muscles

Tests whether a set of muscles is enriched for specific annotations (actions, innervation, body regions) compared to the full set.

Usage

kgEnrichment(
  muscles,
  annotation_type = c("action", "nerve", "body_region", "spinal_level"),
  hub = NULL
)

Arguments

muscles

Character vector of muscle names (query set)

annotation_type

Character; "action", "nerve", "body_region", "spinal_level"

hub

AnnotationHub object

Value

data.frame with term, count, expected, fold_enrichment, p_value

Examples

kgEnrichment(
  c("Trapezius", "Latissimus Dorsi", "Serratus Posterior Superior"),
  annotation_type = "body_region"
)
#>    term count total_in_background  expected fold_enrichment     p_value
#> 1 trunk     3                  47 0.5222222        5.744681 0.004998243